Jodie Foster

Jodie Foster's performance as FBI trainee Clarice Starling in Jonathan Demme's 1991 thriller 'The Silence of the Lambs' earned her a Best Actress Oscar.

However, when Sir Ridley Scott asked her to reprise the role opposite Sir Anthony Hopkins as cannibal killer Dr. Hannibal Lecter for his 2001 sequel 'Hannibal' she said no.

She explained to Total Film at the time: "The official reason I didn't do 'Hannibal' is I was doing another movie, 'Flora Plum.' So, I get to say, in a nice, dignified way, that I wasn't available when that movie was being shot."

The part eventually went to Julianne Moore.