Ross and Rachel...or Joey and Rachel
The whole centrepiece of the 'Friends' is whether Ross and Rachel will get together in a typical will-they-won't-they device. They eventually do, but there was a brief moment in Season 10 where Rachel could have chosen Joey instead. Jennifer later said: "It was Ross and Rachel all the way. I really believe that if there’s an after-world of Friends, they’re still thriving. Don’t you? I just don’t think Joey and Rachel could have made it. I think it was more physical than emotional with them. They were friends with benefits, and they left it at that."