Oscar Isaac
When he signed on to appear in 'X-Men: Apocalypse', Oscar Isaac was thrilled to be playing the movie's main villain, but that enthusiasm quickly dissipated.
The actor had to wear a suit that weighed 40 pounds while he sat in a chair for hours having several layers of glue and latex applied to his face.
Worse still, when these cosmetics were removed, Oscar found it tore of pieces of his skin!
As well as this makeup nightmare, the actor found the actual production of the film a complete disaster, as he spent the majority of the time shooting in front of a green-screen in isolation.