Rachel Adams: The Devil Wears Prada (2006)

Rachel McAdams was the studio’s first choice to play Andy Sachs in The Devil Wears Prada, so much so that she was offered the role three times.

But she turned it down, along with other Hathaway-led films like Get Smart (2008).

Reflecting in a 2018 Bustle interview, McAdams admitted: “I felt guilty for not capitalizing on the opportunity… There were definitely some anxious moments of wondering if I was just throwing it all away. It’s taken years to understand what I intuitively was doing.”