Andre 3000

Andre 3000 was convinced he had morphed into an animal when he drank the brew.

The musician told NPR about his trip which left him thinking he had "turned into a panther".

He explained: "I was actually in Hawaii and it was my second night of the first time I'd ever taken ayahuasca. We did it like a three-night kind of phase. The first night was inviting and beautiful and the most powerful love and connection with all things I've ever felt in my life.

"The second night was different and everybody knows that aya will do you that way. The second night my stomach was hurting, my mouth contorted like a panther and I actually turned into a panther. And I was doing like GRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRR — like, that kind of thing. I actually turned into a panther.

"It was doing this thing called toning. Toning is another way of purging. And toning is where you make these vibrational noises that you can't control.

"It started playing me like an instrument. I started as a panther and then it would make me do these long kind of tones and started changing the notes."