Christina Applegate has found living with multiple sclerosis to be the 'worst thing' she's ever experienced

Hollywood star Christina Applegate has discussed her experience of living with MS.

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Christina Applegate has found living with multiple sclerosis (MS) to be the "worst thing" she's ever experienced.

The 53-year-old actress was diagnosed with MS - a degenerative neurological condition - back in 2021, and Christina admits that living with the autoimmune disease has been the biggest challenge of her life.

During an appearance on the 'Conan O'Brien Needs a Friend' podcast, Christina said: "This is the worst thing I've ever had in my life. It's the worst thing I've ever gone through."

Christina rarely leaves her house these days, as she struggles with her symptoms.

The Hollywood star shared: "If people saw what my life was like on the daily, they wouldn't ... they wouldn't be able to do it. Because I can sometimes not do it. It's really, really hard.

"I don't really leave the house anymore."

MS can cause issues such as muscle weakness, vision changes and numbness.

And Christina admitted that she's experienced "extraordinary" pain since being diagnosed with MS.

She said: "I was losing balance, but the pain was extraordinary. And when I say numb, it's numb, but it hurts."

Christina previously admitted to "screaming" in pain amid her struggles with MS.

The actress revealed the physical toll that the autoimmune disease has taken on her body.

She said on the 'MeSsy' podcast: "I lay in bed screaming - like, the sharp pains, the ache, that squeezing."