Delta Goodrem
The ‘Wings’ hitmaker took on the role of shy schoolgirl Nina Tucker in 2002.
However, Goodrem was diagnosed with Hodgkin's lymphoma and had to leave the show for treatment.
She later returned to tie up Nina’s story - which incorporated Delta's real singing talent - and left 'Neighbours' in 2005 but returned in 2015 for the show’s 30th anniversary.
Delta has had a successful music career releasing seven albums and performing all over the globe.